What should be done if a vaccine is inadvertently frozen?

If a vaccine has been inadvertently frozen, it is critical to discard it unless the manufacturer specifies otherwise. Vaccines are formulated to be stored at specific temperatures to maintain their effectiveness and integrity. Freezing can cause physical changes in the vaccine, such as the formation of ice crystals, which can disrupt the stability of the active ingredients.

Discarding the vaccine ensures that only products that are guaranteed to be effective and safe are administered to patients. The manufacturer's guidelines provide essential information regarding the handling and storage of vaccines, including instructions for what to do if a vaccine has been exposed to inappropriate temperatures. Following these guidelines maintains vaccine efficacy and protects patient safety, making this response the most appropriate action when a vaccine is accidentally frozen.

It is important to note that using a vaccine that has been frozen, assuming it appears normal, poses serious risks to patient health, as the vaccine may no longer provide the intended immune response. Similarly, thawing the vaccine and then storing it does not reverse any potential damage done during the freezing process, which underscores the importance of adhering strictly to storage guidelines provided by manufacturers.